Nouns

(n)substancethe real physical matter of which a person or thing consists“DNA is the substance of our genes”
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(n)kernel, substance, core, center, centre, essence, gist, heart, heart and soul, inwardness, marrow, meat, nub, pith, sum, nitty-grittythe choicest or most essential or most vital part of some idea or experience“the gist of the prosecutor's argument”, “the heart and soul of the Republican Party”, “the nub of the story”
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(n)meaning, substancethe idea that is intended“What is the meaning of this proverb?”
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(n)substancematerial of a particular kind or constitution“the immune response recognizes invading substances”
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(n)means, substanceconsiderable capital (wealth or income)“he is a man of means”
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(n)message, content1, subject matter, substancecontent communicating a message; what something is about
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(n)consistency, consistence, substance, bodythe property of holding together and retaining its shape“wool has more body than rayon”, “when the dough has enough consistency it is ready to bake”
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(n)substancea particular kind or species of matter with uniform properties“shigella is one of the most toxic substances known to man”
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