Nouns

(n)sorean open skin infection

Adjectives

(s)sensitive, sore, raw, tenderhurting“the tender spot on his jaw”
(s)afflictive, painful, sorecausing misery or pain or distress“it was a sore trial to him”, “the painful process of growing up”
(s)huffy, mad, soreroused to anger“stayed huffy a good while” (Mark Twain), “she gets mad when you wake her up so early”, “mad at his friend”, “sore over a remark”