Adjectives

(a)seedyfull of seeds“as seedy as a fig”
(s)scruffy, seedyshabby and untidy“a surge of ragged scruffy children”, “he was soiled and seedy and fragrant with gin” (Mark Twain)
(s)ailing, indisposed, peaked, poorly, sickly, unwell, under the weather, seedysomewhat ill or prone to illness“my poor ailing grandmother”, “feeling a bit indisposed today”, “you look a little peaked”, “feeling poorly”, “a sickly child”, “is unwell and can't come to work”
(s)seamy, seedy, sleazy, sordid, squalidmorally degraded“a seedy district”, “the seamy side of life”, “sleazy characters hanging around casinos”, “sleazy storefronts with … dirt on the walls” (Seattle Weekly), “the sordid details of his orgies stank under his very nostrils” (James Joyce), “the squalid atmosphere of intrigue and betrayal”