Nouns

(n)isolationa state of separation between persons or groups
(n)isolationa feeling of being disliked and alone
(n)isolation, closing offthe act of isolating something; setting something apart from others
(n)isolation(psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it
(n)isolationa country's withdrawal from international politics“he opposed a policy of American isolation”