Verbs

(v)emasculate, castratedeprive of strength or vigor“The Senate emasculated the law”
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(v)emasculate, castrate, demasculinize, demasculiniseremove the testicles of a male animal
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Adjectives

(s)effeminate, emasculate, epicene, cissy, sissified, sissyish, sissyhaving unsuitable feminine qualities
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