dɪˈɹeɪndʒ diˈɹeɪndʒ derange mentally, throw out of mental balance; make insane The death of his parents unbalanced him throw out of balance or equilibrium The tax relief unbalanced the budget The prima donna unbalances the smooth work in our department a lack of balance or state of disequilibrium a hormonal imbalance a state of mental disturbance and disorientation