splaɪs splaɪs ˈwɛd join by interweaving strands Splice the wires join together so as to form new genetic combinations splice genes join the ends of splice film perform a marriage ceremony The minister married us on Saturday We were wed the following week The couple got spliced on Hawaii joint made by overlapping two ends and joining them together a junction where two things (as paper or film or magnetic tape) have been joined together the break was due to an imperfect splice