ˌɪɹɪˈteɪʃən ˌpɹɑvəˈkeɪʃən ˌpɹɒvəˈkeɪʃən action that makes a problem or a disease (or its symptoms) worse the aggravation of her condition resulted from lack of care unfriendly behavior that causes anger or resentment an exasperated feeling of annoyance