grieve
sorrow
feel grief
grief
something that causes great unhappiness
her death was a great grief to John
an emotion of great sadness associated with loss or bereavement
he tried to express his sorrow at her loss
regret
rue
ruefulness
sadness associated with some wrong done or some disappointment
he drank to drown his sorrows
he wrote a note expressing his regret
to his rue, the error cost him the game
sadness
sorrowfulness
the state of being sad
she tired of his perpetual sadness